musica - esquentando a próxima Lista

Ian rogers feat kris layne - what to do with you

medicina - ECOCARDIOGRAMA - gordura epicardica e DAC

Epicardial adipose tissue thickness by echocardiography is a marker for the presence and severity of coronary artery disease

Eroglu S et al. – Epicardial adipose tissue (EAT) thickness, easily and non-invasively evaluated by transthoracic echocardiography, can be an adjunc marker to classic risk factors for prediction of coronary artery disease (CAD). Methods

• Study of whether echocardiographic EAT thickness can serve as a marker for presence and severity of CAD
• Review of 150 pts: 100 CAD pts; 50 with normal coronary arteries by diagnostic coronary angiography
• Subjects: 65 women, 85 men; mean age 55.7±7.4 yrs
• Measurement of EAT thickness by 2-D echocardiographic parasternal long- and short-axis views
• Comparison of EAT thickness measurements with angiographic findings

Results

• EAT thickness significantly higher in CAD pts vs pts with normal coronary arteries (6.9±1.5 mm vs 4.4±0.8 mm)
• EAT thickness increased with severity of CAD: multivessel disease 7.4±1.2 mm vs single vessel disease 5.7±1.7 mm
• Gensini's score significantly correlated with EAT thicknes
• EAT thickness of ≥5.2mm had 85% sensitivity and 81% specificity for predicting CAD

musicas - abalando

ladyhawke - my delirium

Natalie Bassingthwaighte - Someday Soon

Evermore - Hey Boys and Girls (Truth of the World Part 2)

Lesley Roy - Unbeautiful

The Script - Breakeven

medicina - aspirina

Aspirin to Prevent Cardiovascular Disease: The Association of Aspirin Dose and Clopidogrel With Thrombosis and Bleeding

Steven R. Steinhubl, MD; Deepak L. Bhatt, MD, MPH; Danielle M. Brennan, MS; Gilles Montalescot, MD; Graeme J. Hankey, MD; John W. Eikelboom, MB, BS, MSc; Peter B. Berger, MD; and Eric J. Topol, MD, on behalf of the CHARISMA Investigators

Results: Daily aspirin doses were categorized as less than 100 mg (75 or 81 mg) (n = 7180), 100 mg (n = 4961), and greater than 100 mg (150 or 162 mg) (n = 3454). The hazard of the primary efficacy end point was the same regardless of dose (adjusted hazard ratio, 0.95 [95% CI, 0.80 to 1.13] for 100 mg vs. less than 100 mg, and 1.0 [CI, 0.85 to 1.18] for greater than 100 mg vs. less than 100 mg). The hazard of the primary safety end point also did not depend on dose (adjusted hazard ratio, 0.85 [CI, 0.57 to 1.26] for 100 mg vs. less than 100 mg and 1.05 [CI, 0.74 to 1.48] for greater than 100 mg vs. less than 100 mg). In patients also receiving clopidogrel, daily aspirin doses greater than 100 mg seemed to be non–statistically significantly associated with reduced efficacy (adjusted hazard ratio, 1.16 [CI, 0.93 to 1.44]) and increased harm (adjusted hazard ratio, 1.30 [CI, 0.83 to 2.04]).

Limitation: The analysis was post hoc, and aspirin use was not randomized or blinded.

Conclusion: Daily aspirin doses of 100 mg or greater were associated with no clear benefit in patients taking aspirin only and possibly with harm in patients taking clopidogrel. Daily doses of 75 to 81 mg may optimize efficacy and safety for patients requiring aspirin for long-term prevention, especially for those receiving dual antiplatelet therapy.

Context

• The optimal aspirin dose for prevention of cardiovascular events is unknown.
  

Contribution

• This post hoc analysis of CHARISMA trial data suggests no overall differences in efficacy or safety by aspirin dose. However, in the subgroup of patients randomly assigned to clopidogrel, there was a hint of reduced efficacy and increased harm with higher doses.
  

Caution

• Patients were not randomly assigned to aspirin dose.
  

Implication

• Lower aspirin doses (75 to 81 mg/d) may optimize efficacy and safety for patients requiring aspirin for long-term prevention, especially those taking clopidogrel.
  

—The Editors

MUSICA - ba DA lando

Milow - Ayo Technology (P&A Remix)

Mando diao- dance with somebody

MadCon - beggin

David Craig - Insomnia

Deborah Cox - Beautiful U R (Gabi Newman Club Remix)www.clubkings.eu

MUSICA - embalando o domingo

Calvin Harris - I'm Not Alone ( link youtube )

Tinchy Stryder ft. Taio Cruz - Take Me Back

MUSICAS - boas lembranças nesse sábado

Pink - "Sober"
The Fray - "You Found Me"
Kanye West - "Heartless"
Carolina Liar - "Show Me What I'm Looking For"
Lady Gaga - "Poker Face"
Jason Mraz - "Lucky (With Colbie Caillat)"
Plain White T's - "1, 2, 3, 4"
Britney Spears - "Circus"
Lily Allen - "The Fear"
Natasha Bedingfield - "Soulmate"
Gabriella Cilmi - "Sweet About Me"
Missy Higgins - "Where I Stood"
Nickelback - "Gotta Be Somebody"
The Script - "The Man Who Can't Be Moved"
Bruce Springsteen - "The Wrestler"
Sara Bareilles - "Gravity"
Buckcherry - "Don't Go Away"
Erin McCarley - "Love, Save The Empty"
James Morrison - "Broken Strings"
Joshua Radin - "I'd Rather Be With You"
The Ting Tings - "That's Not My Name"
John Legend - "Green Light"
David Cook - "Light On"
The Airborne Toxic Event - "Sometime Around Midnight"
Brett Dennen - "Make You Crazy"
Death Cab For Cutie - "Grapevine Fires"
Oren Lavie - "Her Morning Elegance"

MUSICA - ANIMANDO A SEXTA 13

Flo Rida Feat Katy Perry - Right Round

musica - sugestão ( samba, rock , pagode e criatividade )

Grupo Sambô

É um grupo de Ribeirão Preto , muito bom , criativo , versátil .Tem feito shows em São Paulo
Estou recebendo o CD , e logo passarei para os parceiros divulgarem e postarem.
Sem duvida tem tudo pra estourar......

medicina - teste ergometrico / ST em assimtomaticos

Asymptomatic ST-segment depression during exercise testing and the risk of sudden cardiac death in middle-aged men: a population-based follow-up study

Jari A. Laukkanen^1,2,*, Timo H. Mäkikallio^2,3, Rainer Rauramaa^4,5 and Sudhir Kurl¹

¹ Research Institute of Public Health, University of Kuopio, PO Box 1627, 70211 Kuopio, Finland
² Lapland Central Hospital, Rovaniemi, Finland
³ Division of Cardiology, Department of Internal Medicine, University of Oulu, Oulu, Finland
⁴ Kuopio Research Institute of Exercise Medicine, Kuopio, Finland
⁵ Department of Clinical Physiology and Nuclear Medicine, University Hospital of Kuopio, Kuopio, Finland

Received 12 August 2008; revised 24 November 2008; accepted 11 December 2008; online publish-ahead-of-print 23 January 2009.

^* Corresponding author. Tel: +358 17 162 910, Fax: +358 17 162 936, Email: jariantero.laukkanen@uku.fi

Aims: Silent electrocardiographic ST change predicts future coronary events in patients with coronary heart disease (CHD), but the prognostic significance of asymptomatic ST-segment depression with respect to sudden cardiac death in subjects without apparent CHD is not well known.

Methods and results: We investigated the association between silent ST-segment depression during and after maximal symptom-limited exercise test and the risk of sudden cardiac death in a population-based sample of 1769 men without evident CHD. A total of 72 sudden cardiac death occurred during the median follow-up of 18 years. The risk of sudden cardiac death was increased among men with asymptomatic ST-segment depression during exercise [hazard ratio (HR) 2.1, 95% confidence interval (CI) 1.2–3.9] as well as among those with asymptomatic ST-segment depression during recovery period (HR 3.2, 95% CI 1.7–6.0). Asymptomatic ST-depression during exercise testing was a stronger predictor for the risk of sudden cardiac death especially among smokers as well as in hypercholesterolaemic and hypertensive men than in men without these risk factors.

Conclusion: Asymptomatic ST-segment depression was a very strong predictor of sudden cardiac death in men with any conventional risk factor but no previously diagnosed CHD, emphasizing the value of exercise testing to identify asymptomatic high-risk men who could benefit from preventive measures.

Key Words: Exercise electrocardiography • Sudden death • Risk factors

medicina -consumo de café e mortalidade pós infarto

Coffee consumption and mortality after acute myocardial infarction: The Stockholm Heart Epidemiology Program

Kenneth J. Mukamal, MD, MPHa, Johan Hallqvist, MD, PhDbc, Niklas Hammar, PhDd, Rickard Ljung, MD, MPH, PhDbe, Katalin Gémes, MScbf, Anders Ahlbom, PhDcd, Staffan Ahnve, MD, PhDbc, Imre Janszky, MD, PhDbf

Received 24 September 2008; accepted 17 November 2008. published online 09 January 2009.

Background

Cohort studies have suggested little effect of coffee consumption on risk of acute myocardial infarction. The effect of coffee consumption on prognosis after myocardial infarction is uncertain.

Methods

In a population-based inception cohort study, we followed 1,369 patients hospitalized with a confirmed first acute myocardial infarction between 1992 and 1994 in Stockholm County, Sweden, as part of the Stockholm Heart Epidemiology Program. Participants reported usual coffee consumption over the preceding year with a standardized questionnaire distributed during hospitalization and underwent a health examination 3 months after discharge. Participants were followed for hospitalizations and mortality with national registers through November 2001.

Results

A total of 289 patients died during follow-up. Compared with intake of <1>P trend .06). Coffee intake was not associated with hospitalization for congestive heart failure or stroke. Candidate lipid and inflammatory biomarkers did not appear to account for the observed inverse association with mortality.

Conclusions

Self-reported coffee consumption at the time of hospitalization for myocardial infarction was inversely associated with subsequent postinfarction mortality in this population with broad coffee intake. If confirmed in other settings, identification of relevant mechanisms could lead to an improved prognosis for survivors of acute myocardial infarction.

Musicas - sugestões do dia

No Can Do - Sugababes
Omen - The Prodigy
Love Etc. - Pet Shop Boys ...........................essa tem tudo pra bombar
Sometime Around Midnight - Airborne Toxic Event
Kristy, Are You Doing Okay - The Offspring
No line on the horizon - U2

Medicina - é bom saber ( guia para usuários de anti-coagulantes orais )

Publicado on line na circulation ( 03/03 / 09 ) , acho que sua distribuição livre , é muito importante , devido ao grande numero de usuários dessas substancias

Medicina adiponectina ( 2 )

: J Cardiometab Syndr. 2009 Dec;4(1):44-49.

The Role of Adiponectin in Obesity, Diabetes, and Cardiovascular Disease.

Kawano J, Arora R.

Department of Medicine, Chicago Medical School, North Chicago, IL.

Nearly 1 in 4 adults in the United States is obese. The connection between obesity and insulin resistance, type 2 diabetes, and cardiovascular disease is a well researched one. The increasing prevalence of each of these diseases has become a growing concern for the medical community. Adiponectin is a collagen-like plasma protein secreted by adipocytes that has been suggested to play a causal role in the development of insulin resistance and cardiovascular disease. The protein has been found to be decreased in cases of insulin resistance, diabetes, atherosclerosis, and coronary artery disease. Up-regulation of adiponectin and its receptor, through the use of thiazolidinediones, has been found to be partially related to insulin sensitization and thus antidiabetic effects. In this review, we discuss adiponectin's antiatherogenic effects, its association with insulin resistance and obesity, and the possibility of using adiponectin and its receptor as a therapeutic target.

Medicina - adiponectina

Diabetes Care. 2009 Feb 24. Effect of drinking on adiponectin in healthy men and women: A randomised intervention study of water, ethanol, red wine and beer with or without alcohol.

Imhof A, Plamper I, Maier S, Trischler G, Koenig W.

Dept. of Internal Medicine II, Cardiology, University of Ulm, Ulm, Germany.

Objective: Moderate alcohol consumption is associated with reduced incidence of type 2 diabetes and cardiovascular mortality and increases adiponectin concentrations but effects might be differ according to gender and beverage consumed. Research design and methods: Seventy-two healthy individuals (22-56 years) were enrolled in this randomised controlled cross-over trial. After wash-out, two interventions for 3 weeks followed: ethanol (concentration 12.5 %), beer (5.6 %), or red wine (12.5 %) equivalent to 30 grams of ethanol per day for men and 20 g/d for women or the same de-alcoholised beverages, or water. Adiponectin was measured by sandwich ELISA. Results: Among females adiponectin significantly increased after with red wine (29,8% p<0.05),>