Medicina - adiponectina

Diabetes Care. 2009 Feb 24. Effect of drinking on adiponectin in healthy men and women: A randomised intervention study of water, ethanol, red wine and beer with or without alcohol.

Imhof A, Plamper I, Maier S, Trischler G, Koenig W.

Dept. of Internal Medicine II, Cardiology, University of Ulm, Ulm, Germany.

Objective: Moderate alcohol consumption is associated with reduced incidence of type 2 diabetes and cardiovascular mortality and increases adiponectin concentrations but effects might be differ according to gender and beverage consumed. Research design and methods: Seventy-two healthy individuals (22-56 years) were enrolled in this randomised controlled cross-over trial. After wash-out, two interventions for 3 weeks followed: ethanol (concentration 12.5 %), beer (5.6 %), or red wine (12.5 %) equivalent to 30 grams of ethanol per day for men and 20 g/d for women or the same de-alcoholised beverages, or water. Adiponectin was measured by sandwich ELISA. Results: Among females adiponectin significantly increased after with red wine (29,8% p<0.05),>