medicina - ECOCARDIOGRAMA - gordura epicardica e DAC

Epicardial adipose tissue thickness by echocardiography is a marker for the presence and severity of coronary artery disease

Eroglu S et al. – Epicardial adipose tissue (EAT) thickness, easily and non-invasively evaluated by transthoracic echocardiography, can be an adjunc marker to classic risk factors for prediction of coronary artery disease (CAD). Methods

• Study of whether echocardiographic EAT thickness can serve as a marker for presence and severity of CAD
• Review of 150 pts: 100 CAD pts; 50 with normal coronary arteries by diagnostic coronary angiography
• Subjects: 65 women, 85 men; mean age 55.7±7.4 yrs
• Measurement of EAT thickness by 2-D echocardiographic parasternal long- and short-axis views
• Comparison of EAT thickness measurements with angiographic findings

Results

• EAT thickness significantly higher in CAD pts vs pts with normal coronary arteries (6.9±1.5 mm vs 4.4±0.8 mm)
• EAT thickness increased with severity of CAD: multivessel disease 7.4±1.2 mm vs single vessel disease 5.7±1.7 mm
• Gensini's score significantly correlated with EAT thicknes
• EAT thickness of ≥5.2mm had 85% sensitivity and 81% specificity for predicting CAD